Asst. Prof. Lalehan Akyuz

Asst. Prof. Lalehan Akyuz

Asst. Prof. Lalehan Akyuz

Education Information

Graduate

Erciyes University, Faculty of Science, Department of Chemistry,

01.09.1999-01.07.2003.

Master

Erciyes University, Institute of Science, Chemistry,

01.09.2003-01.07.2005.

Thesis Title: 2-amino-6-arilsülfonil Benzonitril Bilesiklerinin Hiv-1
Inhibitörü Olarak Comcet Yöntemi Ile Qsar Incelemesi
Thesis Subject: 2-amino-6-arilsülfonil Benzonitril Bişlesiklerinin Hiv-1 Inhibitörü Olarak Comcet Yöntemi Ile Qsar Incelemesi

Doktora

Erciyes University, Institute of Science, Chemistry,

01.09.2005-01.02.2011.

Thesis Title: Anti-hiv Etkili Hept, Tibo, Tiyazolidin Ve Dabo Türevlerinin Elektron Konformasyonel-genetik Algoritma Metodu Kullanılarak Yeni Bir 4dqsar Yöntemi Ile Aktif Gruplarinin Belirlenmesi

Thesis Subject: Anti-hiv Etkili Hept, Tibo, Tiyazolidin Ve Dabo Türevlerinin Elektron Konformasyonel-genetik Algoritma Metodu Kullanılarak Yeni Bir 4dqsar Yöntemi Ile Aktif Gruplarinin Belirlenmesi

Experience Information

01 June 2014 – Now (Full Time)

Asst. Prof. Aksaray Unıversıtesı, Aksaray Tecnıcal Scıences Vocatıonal School, Chemıcal Technology Program.

Administrative Job: Head of Departmens

Foreign Language Information

English

Articles

1. S. KHADEM, M. KAYA, Y. S. CAKMAK, M. MUJTABA, S. ILK, L. AKYUZ, A. M. SALABERRIA, J. LABIDI, A. H. ABDULQADIR & E. DELIGOZ, Antioxidative and antimicrobial edible chitosan films blended with stem, leaf and seed extracts of Pistacia terebinthus for active food packaging, RSC ADVANCES, 2018, 2046-2069, 8, 8, 3941-3950.
2. L. AKYUZ, M. KAYA, S. ILK, Y. S. CAKMAK, A. M. SALABERRIA, J. LABIDI, B. A. YILMAZ & I. SARGIN, Effect of different animal fat and plant oil additives on physicochemical, mechanical, antimicrobial and antioxidant properties of chitosan films, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 0141-8130, 111, 475-484.
3. S. ILK, M. MUJTABA, M. GURSOY, I. SARGIN, B. AKYUZ, N. ERDEM, L. AKYUZ, M. KAYA, Y. S. CAKMAK, A. M. SALABERRIA & J. LABIDI, False flax (Camelina sativa) seed oil as suitable ingredient for the enhancement of physicochemical and biological properties of chitosan films, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 0141-8130, 114, 1224-1232.
4. M. KAYA, P. RAVIKUMAR, S. ILK, M. MUJTABA, L. AKYUZ, J. LABIDI, A. M. SALABERRIA, Y. S. CAKMAK & S. K. ERKUL, Production and characterization of chitosan based edible films from Berberis crataegina’s fruit extract and seed oil, INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES, 2018, 1466-8564, 45, 287-297.
5. L. AKYUZ, I. SARGIN, M. KAYA, T. CETER & I. AKATA, A new pollen-derived microcarrier for pantoprazole delivery, MATERIALS SCIENCE & ENGINEERING CMATERIALS FOR BIOLOGICAL APPLICATIONS, 2017, 0928-4931, 71, 937-942.
6. I. SARGIN, L. AKYUZ, M. KAYA, G. TAN, T. CETER, K. YILDIRIM, S. ERTOSUN, G. H. AYDIN & M. TOPAL, Controlled release and anti-proliferative effect of imatinib mesylate loaded sporopollenin microcapsules extracted from pollens of Betula pendula, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2017, 0141-8130, 105, 749-756.
7. M. MUJTABA, M. KAYA, L. AKYUZ, D. ERDONMEZ, B. AKYUZ & I. SARGIN, Detailed adsorption mechanism of plasmid DNA by newly isolated cellulose from waste flower spikes of Thypa latifolia using quantum chemical calculations, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2017, 0141- 8130, 102, 914-923.
8. L. AKYUZ, M. KAYA, B. KOC, M. MUJTABA, S. ILK, J. LABIDI, A. M. SALABERRIA, Y. S. CAKMAK & A. YILDIZ, Diatomite as a novel composite ingredient for chitosan film with enhanced physicochemical properties, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2017, 0141-8130, 105, 1401-1411.
9. L. AKYUZ, F. DUMAN & M. KAYA, Encapsulation of Flurbiprofen by Chitosan Using a Spray-Drying Method with In Vitro Drug Releasing and Molecular Docking, TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 1304-530X, 14, 1, 34-39.
10. L. AKYUZ, M. KAYA, I. SARGIN, M. MUJTABA, A. M. SALABERRIA, J. LABIDI, Y. S. CAKMAK, B. KOC, T. BARAN & T. CETER, Incorporation of sporopollenin enhances acid-base durability, hydrophobicity, and mechanical, antifungal and antioxidant properties of chitosan films, JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 2017, 1226-086X, 47, 236-245.
11. M. MUJTABA, I. SARGIN, L. AKYUZ, T. CETER & M. KAYA, Newly isolated sporopollenin microcages from Platanus orientalis pollens as a vehicle for controlled drug delivery, MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2017, 0928-4931, 77, 263-270.
12. M. KAYA, M. MUJTABA, H. EHRLICH, A. M. SALABERRIA, T. BARAN, C. T. AMEMIYA, R. GALLI, L. AKYUZ, I. SARGIN & J. LABIDI, On chemistry of gamma-chitin,CARBOHYDRATE POLYMERS, 2017, 0144-8617, 176, 177-186.
13. L. AKYUZ, L. AKYUZ, E. SARIPINAR & E. SARIPINAR, Conformation depends on 4DQSAR analysis using EC-GA method: pharmacophore identification and bioactivity prediction of TIBOs as non-nucleoside reverse transcriptase inhibitors, JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2013, 1475-6366, 28, 4, 776-791.
14. N. OZDEMIR, N. OZDEMIR, E. INKAYA, E. INKAYA, E. SARIPINAR, E. SARIPINAR, L. AKYUZ, L. AKYUZ, I. O. ILHAN, I. O. ILHAN, S. AYDIN, S. AYDIN, M. DINCER, M. DINCER, O. BUYUKGUNGOR & O. BUYUKGUNGOR, Synthesis, spectroscopic (FTIR/ NMR) characterization, X-ray structure and DFT studies on (E)-2-(1- phenylethylidene) hydrazinecarboximidamide nitrate hemimethanol, SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2013, 1386-1425, 114, 175-182.
15. L. AKYUZ, L. AKYUZ, E. SARPINAR, E. SARPINAR, E. KAYA, E. KAYA, E. YANMAZ & E. YANMAZ, 4D-QSAR study of HEPT derivatives by electron conformational-genetic algorithm method, SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2012, 1062- 936X, 23, 5-6, 409-433.
16. L. AKYÜZ, M. DINÇER, M. DINÇER, N. ÖZDEMIR, N. ÖZDEMIR, E. SARIPINAR, E. SARIPINAR, E. KULAK, E. KULAK, O. BÜYÜKGÜNGÖR & O. BÜYÜKGÜNGÖR, N-(2,4- Dimethoxybenzylideneamino)- guanidinium dihydrogenphosphate, ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 2005, 0108-2701, C61, -, 722-724.

Conference Papers

1. L. AKYÜZ, I. SARGIN, M. KAYA, T. CETER & I. AKATA, A New Pollen-derived Microcarrier For Pantoprazole Delivery, Sözlü Sunum, Bau Drug Design, 13 October 2016, 15 October 2016.
2. L. AKYÜZ, Hept Türevlerinin Elektron Konformasyonel genetik Algoritma Metodu Nicel Yapi Aktivite Iliskisinin Incelenmesi, Poster Sunumu, 25. Uluslararasi Katilimli Ulusal Kimya Kongresi?, 25 June 2011, 25 June 2011.
3. L. AKYÜZ, Tibo Türevlerinin Elektron Konformasyonel-genetik Algoritma Metodu Ile Aktif Gruplarinin Belirlenmesi? Ve Biyoaktivite Tahmini, Sözlü Sunum, 25. Uluslararasi Katilimli Ulusal Kimya Kongresi, 25 June 2011, 25 June 2011.
4. E. SARIPINAR, L. AKYÜZ & E. KAYA, Identification Of Pharmacophore Groups And Bioactivity Calculation Of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio) Thymine (hept) By Electron Conformational Qsar Method, Poster Sunumu, The 8th International Conference On Chemical Physics, 24 April 2008, 24 April 2008.
5. L. AKYÜZ, 1-[(2-hidroksimethoksi)metil]-6-(feniltiyo)timin (hept) Bilesiklerinin Hiv-1 Inhibitörü Olarak Comcet Yöntemi Ile Qsar Incelemesi, Poster Sunumu, Xx. Ulusal Kimya Kongresi, 04 September 2006, 04 September 2006.
6. Y. GUZEL, E. SARIPINAR & L. AKYÜZ, Qsar Study Of Hiv-1 Reverse Transcriptase Inhibitor 2-amino-6-arylsulfonylbenzonitriles Derivatives, Poster Sunumu, International Symposium On Medicinal Chemistry Research And Development, 28 September 2005, 28 September 2005.

Projects

1. KURUMSAL (BAP V.B.), PROJE YÜRÜTÜCÜSÜ, Farklı Hayvansal Ve Bitkisel Yag Katkılarının Kitosan Filmlerin Fizikokimyasal, Mekanik, Antimikrobiyal Ve Antioksidan Özelliklerine Etkisi, Enforcing Institution: AKSARAY ÜNIVERSITESI, 01 March 2017, 01 September 2017.
2. KURUMSAL (BAP V.B.), ARASTIRMACI, Farklı Oranlarda Ketencik Tohumu Yagı Kullanılarak Üretilen Kitosan Temelli Filmlerin Antimikrobiyal Ve Antioksidan Özelliklerinin Belirlenmesi, Enforcing Institution: AKSARAY ÜNIVERSITESI, 01 March 2017, 01 September 2017.
3. KURUMSAL (BAP V.B.), ARASTIRMACI, Vakum Metalize Yöntemiyle Alüminyum Kaplanan Farklı Plastik Reflektörlerin Bir Ameliyathane Tavan Lambasının Led Modülündeki Reflektif Performansının Incelenmesi, Enforcing Institution:
   AKSARAY ÜNIVERSITESI, 01 May 2016, 01 July 2017.
4. DIGER, DANISMAN, NITRIL KAPLAMA ELDIVEN IMALATINDA AR-GE ÇALISMALARIYLA YENI VE NITELIKLI ÜRÜN GELISTIRILMESI, Enforcing Institution: KURULUS GÜNCELLENMESI GEREKIYOR, Sponsor Institution: DIGER (Yurt Içi) , 15 May 2015, 15 May 2016.
5. BAP, PROJE YÜRÜTÜCÜSÜ, FLURBIPROFENIN KITOSAN ILE ENKAPSÜLASYONÖZELLIKLERININ INCELENMESI ,  Enforcing Institution: KURULUS GÜNCELLENMESI
   GEREKIYOR, Sponsor Institution: DIGER (Yurt Içi) , 01 April 2015, 01 April 2016.
6. ULUSAL, BURSIYER, 1-[(2-HYDROXYETHOXY) METHYL]-6-(PHENYLTHIO) THYMINE(HEPT) BILESIKLERININ HIV-1 INHIBITÖRÜ OLARAK COMCET YÖNTEMI ILE QSAR INCELEMESI, Enforcing Institution: KURULUS GÜNCELLENMESI GEREKIYOR, Sponsor Institution: , 01 May 2006, 01 May 2008.
7. BAP, ARASTIRMACI, HIV-1 INHIBITÖRÜ OLAN 2,3-DIARIL-1,3-TIYAZOLIDIN-4-ON TÜREVLERININ PM3-ELEKTRON TOPOLOJIK METOT ILE INCELENMESI, Enforcing
   Institution: KURULUS GÜNCELLENMESI GEREKIYOR, Sponsor Institution: DIGER (Yurt Içi) , 01 May 2005, 01 May 2007.