Asst. Prof. Lalehan Akyuz
Education Information
Graduate
Erciyes University, Faculty of Science, Department of Chemistry,
01.09.1999-01.07.2003.
Master
Erciyes University, Institute of Science, Chemistry,
01.09.2003-01.07.2005.
Thesis Title: 2-amino-6-arilsülfonil Benzonitril Bilesiklerinin Hiv-1
Inhibitörü Olarak Comcet Yöntemi Ile Qsar Incelemesi
Thesis Subject: 2-amino-6-arilsülfonil Benzonitril Bişlesiklerinin Hiv-1 Inhibitörü Olarak Comcet Yöntemi Ile Qsar Incelemesi
Doktora
Erciyes University, Institute of Science, Chemistry,
01.09.2005-01.02.2011.
Thesis Title: Anti-hiv Etkili Hept, Tibo, Tiyazolidin Ve Dabo Türevlerinin Elektron Konformasyonel-genetik Algoritma Metodu Kullanılarak Yeni Bir 4dqsar Yöntemi Ile Aktif Gruplarinin Belirlenmesi
Thesis Subject: Anti-hiv Etkili Hept, Tibo, Tiyazolidin Ve Dabo Türevlerinin Elektron Konformasyonel-genetik Algoritma Metodu Kullanılarak Yeni Bir 4dqsar Yöntemi Ile Aktif Gruplarinin Belirlenmesi
Experience Information
01 June 2014 – Now (Full Time)
Asst. Prof. Aksaray Unıversıtesı, Aksaray Tecnıcal Scıences Vocatıonal School, Chemıcal Technology Program.
Administrative Job: Head of Departmens
Foreign Language Information
English
Articles
- S. KHADEM, M. KAYA, Y. S. CAKMAK, M. MUJTABA, S. ILK, L. AKYUZ, A. M. SALABERRIA, J. LABIDI, A. H. ABDULQADIR & E. DELIGOZ, Antioxidative and antimicrobial edible chitosan films blended with stem, leaf and seed extracts of Pistacia terebinthus for active food packaging, RSC ADVANCES, 2018, 2046-2069, 8, 8, 3941-3950.
- L. AKYUZ, M. KAYA, S. ILK, Y. S. CAKMAK, A. M. SALABERRIA, J. LABIDI, B. A. YILMAZ & I. SARGIN, Effect of different animal fat and plant oil additives on physicochemical, mechanical, antimicrobial and antioxidant properties of chitosan films, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 0141-8130, 111, 475-484.
- S. ILK, M. MUJTABA, M. GURSOY, I. SARGIN, B. AKYUZ, N. ERDEM, L. AKYUZ, M. KAYA, Y. S. CAKMAK, A. M. SALABERRIA & J. LABIDI, False flax (Camelina sativa) seed oil as suitable ingredient for the enhancement of physicochemical and biological properties of chitosan films, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 0141-8130, 114, 1224-1232.
- M. KAYA, P. RAVIKUMAR, S. ILK, M. MUJTABA, L. AKYUZ, J. LABIDI, A. M. SALABERRIA, Y. S. CAKMAK & S. K. ERKUL, Production and characterization of chitosan based edible films from Berberis crataegina’s fruit extract and seed oil, INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES, 2018, 1466-8564, 45, 287-297.
- L. AKYUZ, I. SARGIN, M. KAYA, T. CETER & I. AKATA, A new pollen-derived microcarrier for pantoprazole delivery, MATERIALS SCIENCE & ENGINEERING CMATERIALS FOR BIOLOGICAL APPLICATIONS, 2017, 0928-4931, 71, 937-942.
- I. SARGIN, L. AKYUZ, M. KAYA, G. TAN, T. CETER, K. YILDIRIM, S. ERTOSUN, G. H. AYDIN & M. TOPAL, Controlled release and anti-proliferative effect of imatinib mesylate loaded sporopollenin microcapsules extracted from pollens of Betula pendula, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2017, 0141-8130, 105, 749-756.
- M. MUJTABA, M. KAYA, L. AKYUZ, D. ERDONMEZ, B. AKYUZ & I. SARGIN, Detailed adsorption mechanism of plasmid DNA by newly isolated cellulose from waste flower spikes of Thypa latifolia using quantum chemical calculations, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2017, 0141- 8130, 102, 914-923.
- L. AKYUZ, M. KAYA, B. KOC, M. MUJTABA, S. ILK, J. LABIDI, A. M. SALABERRIA, Y. S. CAKMAK & A. YILDIZ, Diatomite as a novel composite ingredient for chitosan film with enhanced physicochemical properties, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2017, 0141-8130, 105, 1401-1411.
- L. AKYUZ, F. DUMAN & M. KAYA, Encapsulation of Flurbiprofen by Chitosan Using a Spray-Drying Method with In Vitro Drug Releasing and Molecular Docking, TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 1304-530X, 14, 1, 34-39.
- L. AKYUZ, M. KAYA, I. SARGIN, M. MUJTABA, A. M. SALABERRIA, J. LABIDI, Y. S. CAKMAK, B. KOC, T. BARAN & T. CETER, Incorporation of sporopollenin enhances acid-base durability, hydrophobicity, and mechanical, antifungal and antioxidant properties of chitosan films, JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 2017, 1226-086X, 47, 236-245.
- M. MUJTABA, I. SARGIN, L. AKYUZ, T. CETER & M. KAYA, Newly isolated sporopollenin microcages from Platanus orientalis pollens as a vehicle for controlled drug delivery, MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2017, 0928-4931, 77, 263-270.
- M. KAYA, M. MUJTABA, H. EHRLICH, A. M. SALABERRIA, T. BARAN, C. T. AMEMIYA, R. GALLI, L. AKYUZ, I. SARGIN & J. LABIDI, On chemistry of gamma-chitin,CARBOHYDRATE POLYMERS, 2017, 0144-8617, 176, 177-186.
- L. AKYUZ, L. AKYUZ, E. SARIPINAR & E. SARIPINAR, Conformation depends on 4DQSAR analysis using EC-GA method: pharmacophore identification and bioactivity prediction of TIBOs as non-nucleoside reverse transcriptase inhibitors, JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2013, 1475-6366, 28, 4, 776-791.
- N. OZDEMIR, N. OZDEMIR, E. INKAYA, E. INKAYA, E. SARIPINAR, E. SARIPINAR, L. AKYUZ, L. AKYUZ, I. O. ILHAN, I. O. ILHAN, S. AYDIN, S. AYDIN, M. DINCER, M. DINCER, O. BUYUKGUNGOR & O. BUYUKGUNGOR, Synthesis, spectroscopic (FTIR/ NMR) characterization, X-ray structure and DFT studies on (E)-2-(1- phenylethylidene) hydrazinecarboximidamide nitrate hemimethanol, SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2013, 1386-1425, 114, 175-182.
- L. AKYUZ, L. AKYUZ, E. SARPINAR, E. SARPINAR, E. KAYA, E. KAYA, E. YANMAZ & E. YANMAZ, 4D-QSAR study of HEPT derivatives by electron conformational-genetic algorithm method, SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2012, 1062- 936X, 23, 5-6, 409-433.
- L. AKYÜZ, M. DINÇER, M. DINÇER, N. ÖZDEMIR, N. ÖZDEMIR, E. SARIPINAR, E. SARIPINAR, E. KULAK, E. KULAK, O. BÜYÜKGÜNGÖR & O. BÜYÜKGÜNGÖR, N-(2,4- Dimethoxybenzylideneamino)- guanidinium dihydrogenphosphate, ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 2005, 0108-2701, C61, -, 722-724.
Conference Papers
- L. AKYÜZ, I. SARGIN, M. KAYA, T. CETER & I. AKATA, A New Pollen-derived Microcarrier For Pantoprazole Delivery, Sözlü Sunum, Bau Drug Design, 13 October 2016, 15 October 2016.
- L. AKYÜZ, Hept Türevlerinin Elektron Konformasyonel genetik Algoritma Metodu Nicel Yapi Aktivite Iliskisinin Incelenmesi, Poster Sunumu, 25. Uluslararasi Katilimli Ulusal Kimya Kongresi?, 25 June 2011, 25 June 2011.
- L. AKYÜZ, Tibo Türevlerinin Elektron Konformasyonel-genetik Algoritma Metodu Ile Aktif Gruplarinin Belirlenmesi? Ve Biyoaktivite Tahmini, Sözlü Sunum, 25. Uluslararasi Katilimli Ulusal Kimya Kongresi, 25 June 2011, 25 June 2011.
- E. SARIPINAR, L. AKYÜZ & E. KAYA, Identification Of Pharmacophore Groups And Bioactivity Calculation Of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio) Thymine (hept) By Electron Conformational Qsar Method, Poster Sunumu, The 8th International Conference On Chemical Physics, 24 April 2008, 24 April 2008.
- L. AKYÜZ, 1-[(2-hidroksimethoksi)metil]-6-(feniltiyo)timin (hept) Bilesiklerinin Hiv-1 Inhibitörü Olarak Comcet Yöntemi Ile Qsar Incelemesi, Poster Sunumu, Xx. Ulusal Kimya Kongresi, 04 September 2006, 04 September 2006.
- Y. GUZEL, E. SARIPINAR & L. AKYÜZ, Qsar Study Of Hiv-1 Reverse Transcriptase Inhibitor 2-amino-6-arylsulfonylbenzonitriles Derivatives, Poster Sunumu, International Symposium On Medicinal Chemistry Research And Development, 28 September 2005, 28 September 2005.
Projects
- KURUMSAL (BAP V.B.), PROJE YÜRÜTÜCÜSÜ, Farklı Hayvansal Ve Bitkisel Yag Katkılarının Kitosan Filmlerin Fizikokimyasal, Mekanik, Antimikrobiyal Ve Antioksidan Özelliklerine Etkisi, Enforcing Institution: AKSARAY ÜNIVERSITESI, 01 March 2017, 01 September 2017.
- KURUMSAL (BAP V.B.), ARASTIRMACI, Farklı Oranlarda Ketencik Tohumu Yagı Kullanılarak Üretilen Kitosan Temelli Filmlerin Antimikrobiyal Ve Antioksidan Özelliklerinin Belirlenmesi, Enforcing Institution: AKSARAY ÜNIVERSITESI, 01 March 2017, 01 September 2017.
- KURUMSAL (BAP V.B.), ARASTIRMACI, Vakum Metalize Yöntemiyle Alüminyum Kaplanan Farklı Plastik Reflektörlerin Bir Ameliyathane Tavan Lambasının Led Modülündeki Reflektif Performansının Incelenmesi, Enforcing Institution:
AKSARAY ÜNIVERSITESI, 01 May 2016, 01 July 2017. - DIGER, DANISMAN, NITRIL KAPLAMA ELDIVEN IMALATINDA AR-GE ÇALISMALARIYLA YENI VE NITELIKLI ÜRÜN GELISTIRILMESI, Enforcing Institution: KURULUS GÜNCELLENMESI GEREKIYOR, Sponsor Institution: DIGER (Yurt Içi) , 15 May 2015, 15 May 2016.
- BAP, PROJE YÜRÜTÜCÜSÜ, FLURBIPROFENIN KITOSAN ILE ENKAPSÜLASYONÖZELLIKLERININ INCELENMESI , Enforcing Institution: KURULUS GÜNCELLENMESI
GEREKIYOR, Sponsor Institution: DIGER (Yurt Içi) , 01 April 2015, 01 April 2016. - ULUSAL, BURSIYER, 1-[(2-HYDROXYETHOXY) METHYL]-6-(PHENYLTHIO) THYMINE(HEPT) BILESIKLERININ HIV-1 INHIBITÖRÜ OLARAK COMCET YÖNTEMI ILE QSAR INCELEMESI, Enforcing Institution: KURULUS GÜNCELLENMESI GEREKIYOR, Sponsor Institution: , 01 May 2006, 01 May 2008.
- BAP, ARASTIRMACI, HIV-1 INHIBITÖRÜ OLAN 2,3-DIARIL-1,3-TIYAZOLIDIN-4-ON TÜREVLERININ PM3-ELEKTRON TOPOLOJIK METOT ILE INCELENMESI, Enforcing
Institution: KURULUS GÜNCELLENMESI GEREKIYOR, Sponsor Institution: DIGER (Yurt Içi) , 01 May 2005, 01 May 2007.
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